|
|
Testosterone, an androgen, stimulates the growth
and development of male sexual characteristics such as facial hair, muscles,
bones, weight of kidney, genitals, prostrate,etc. Two dominant female estrogen
are estradiol and estrone. Both of these and all the synthetic analogs
which are used in birth control pills have a common chemical structure
of steroids with phenolic end groups.
The menstruation cycle in adult female body begins
with the pituitary gland releasing follicle stimulating hormone (FSH) which
is stimulating and sustaining the growth of one egg in the ovary. The sack
surrounding an egg secretes estrogen hormones to prepare the lining of
the uterus to receive the fertilized egg. A high level of synthetic estrogen
and progesterone put in female body shall halt the production of FSH hormone
resulting in no formation of either eggs or egg follicles in the uterus
to receive fertilized egg. Thus the adult female will not become pregnant
or her pregnancy ( conception ) will be short-lived or aborted.
Estrogens are strong growth promoters of normal
and most cancerous breast tissue and the population of estrogen receptors
and cancerous cells were seen to be correlated with the level of estrogen
in blood stream.
Most known risk factors for breast cancer are
attributable to some form of estrogen overexposure (see below).
Estradiol ( an estrogen ) increases 20 times higher
during the first trimester of a normal pregnancy. If the pregnancy is completed,
the growth of breast tissues is halted and replaced with milk-producing
tissues. Thus, if pregnancy is stopped short by abortion or breast-feeding
is not used, the excessive estrogen level in blood shall promote breast
tissues to growth abnormally into cancerous cells.
Pregnancies which are terminated spontaneously
or naturally usually do not pose this problem as they tend to associate
with very abnormally low estrogen level.
Clinical rats which were forced with abortions
were seen to develop more breast cancers dramatically.
The natural estrogen and progesterone could be
used as a contraceptive but they have to be administered via injection
as they are metabolized or oxidized quickly while the synthetic analogs
which have slightly different chemical structures are not. Unfortunately
the latter also can accumulate in human body much longer.
Besides, the level of the natural estrogen in
adult female body is normally about 2 - 20 ppt ( part per trillion ) based
on her body weight, a very very minute amount compared to 0.1 mg - 2.0
mgs in BC pills, which amounts to about 300,000 ppt totally for a woman
who weighs 160 pounds . And we already knew as concrete biological facts
that abortion was linked to the significant increase in breast cancer due
to the excessive accumulation of the natural of estrogen of only 40 to
500 ppt or 20 times higher than the normal level. How much more damaging
will the birth control pill be to woman body?
( You shall see later a much lower dose of estrogen-like chemicals at 2,000
ppt is already enough to produce abnormality in the reproductive system
of clinical rats).
Thus bombarding the developing embryo in its very
early stage with such massive dose of estrogen shall cause severe and irreversible
damages on the child's reproductive system and this can lead to birth defect
and child and adult cancers later on.
Misoprostol ( Cyclotec ) is a prostaglandin used
to treat ulcer, a hormone-like chemical which was already mentioned previously.
1. Substances " known to be human carcinogens
" which showed to be cancer-causing
The 1994 NTP Report included the following as
carcinogens:
- Conjugated estrogen,
Some of these are naturally occurring hormones
which are practically safe at very minute level (part per trillion ) existing
naturally in human body. However, if these hormones especially the synthetic
ones are introduced into human bodies as contraceptive and abortion chemicals
at such massive doses as the ones in birth control pills or RU-486, many
dangerous side-effects including cancers to both mother and her offspring's
might occur. Also one should remember the accumulation effect of the synthetic
hormones which were particularly developed to be long lasting and stable
for an oral intake to be possible.
During the last two years, the alarming issue
of estrogen mimicking has been surfaced in which many man-made chemicals
which resembled estrogen were tested or suspected to be carcinogenic to
clinical animals and their offspring's, and the sex and reproductive organs
were the most vulnerable! This issue shall be explored further in the next
section.
Thus the presently available contraceptive and
abortifacient " drugs " can vary somewhat in chemical structures from the
natural occurring or carcinogenic ones. However, to be effective, they
all have to function similarly to estrogen therefore, possibly produce
the same adverse side-effects as much weaker estrogen-mimicking substances
do.
Endocrine systems in human include brain, reproductive
organs, sex organs, glands, hormones, hormone receptors.
Estrogens can also exist in environment such as
phytoestrogens which exist in very large quantities in wheat, oat, rye,
soybean ... but these are proved to be beneficial and might have anti-cancer
effects.
In-utero exposure is most sensitive and can be
tragic to fetal development in terms of sexual disorientation, abnormality
in endocrine systems which are irreversible and damaging in most cases.
During 1940-1960, about 40 millions women were introduced with DES, a synthetic
estrogen mimicking chemical. The DES sons and daughters were found in 1970's
to have many abnormalities in reproductive systems and testicle cancer.
The natural levels of natural estrogen in human
body are very low , 2- 25 parts per trillion compared to 100,000 to 10,000,000
parts per trillion in doses of contraceptive and abortifacient chemicals.
And the synthetic hormones are not readily consumed by human body. Also
timing for these potent chemicals to be introduced to human body is very
critical and for the most part is not well understood.
Since early 1960 European sperm count reduced
about 50% and breast cancer, cervix and prostrate cancers increased roughly
50% also during the same period in which birth control pills were introduced.
Some contributed these phenomena to environmental pollution, however, the
populations in Poland and Eastern European countries had a lower cancer
rates than those in Western Europe!
In 1989 the European community banned all US beef
which was produced with growth hormones, i.e., estrogen as they deemed
the product was cancerous. The residual level of hormones was measured
to be about 0.6-1.0 ppb or 600-1,000 ppt. However, the same Europeans are
still taking daily and willingly birth control pills which contain much
higher levels of estrogen than in US beef ! The level is estimated to be
100 to 1,000 times higher than in beef growed with synthetic hormones.
The numbers of boys born with a defect in urinary
opening which is not at the end of the penis nearly doubled in the United
States between 1970 and 1993. Hypospadias affects 1 of every 100 newborn
boys. The cause of the defect is believed to be linked to an insufficient
surge of testosterone 9 to 12 weeks after conception ( remember that testosterone
is key to the development of the male reproductive system). The unusually
low level of testosterone is probably due to the high level of residual
androgen or progestogen the baby's mother takes with her birth control
pills. Several studies in the 1970s seemed to confirm this. A 1967 study
found that progestin causes the defect in rats.
The increasing infertility in Western women is
probably due in part to the artificial high levels of estrogen or hormones
in their bodies of which physiological response toward hormones has also
irreversibly changed.
The cancer rate in Japan is much lower than other
industrial countries, not due to the soybean they ate but more than likely
due to the much less premarital sex and contraception being practiced.
Deformed frogs were found in Minnesota and Wisconsin,
possibly linked to estrogen-mimicking insecticides.
Researchers from Tulane University found that
estrogen mimicking substances alone or in combination affected alligators'
sex hormones.
DDT and dicofol caused major reproductive problems
among alligators ( low sperm count and shrinking penis ) in Florida's Lake
Apopaka ( C & EN May 13, 1996).
Prostate cancer is seen dramatically increased
according to National Cancer Institute, the second most leading cancer.
PCB ( poly chlorinated biphenyls ) was painted
on turtle eggs and the sex of the hatched eggs were reversed. And mixtures
of various PCB's at lower concentrations produced the same effect.
Estrogen-mimicking of Bisphenol A:
(C & EN 3/29/97)
This experimental study was conducted by Vom Saal,
et. al. from University of Missouri. Small doses of BPA were given to pregnant
mice for seven days and the adult male offsprings had enlarged prostrates
of 30% enlarged. The dose used was 2 micron gram per kg body weight or
2 part per billion (ppb) or 2000 parts per trillion (ppt). As we recall,
a modern Western woman consumes about 200,000 ppt per dose of birth-control
pills which contain the more potent estrogen themselves!
The result in mice is considered very relevant
to human as there is not much evidence thus far to contradict this belief.
Vom Saal and company also studied the natural
estrogen estradiol and synthetic like DES and the results were the same
in mice.
Effects of estrogen mimicks on testing animals:
-Disrupting endocrine systems,
Some of these symptoms were also observed in humans.
Many cancer-causing chemicals or carcinogens
promote cancerous growths by interfering with this replication process
and ultimately the cell division (process) in a human body. A carcinogen
reacts or bonds chemically with various sites on DNA helix. Doing so, it
will alter the propagation of the newly-formed DNA molecules and their
embedded genetic codes.
Medicinal chemists from University of
Illinois Chicago recently discovered that the by-product of the metabolism
of estrogen could form a stable but potentially damaging adduct with DNA
molecules ( http://pubs.acs.org/journals/crtoec/). Assistant Professor
Judy Bolton and her group found that the metabolism of equilenin, an estrogen
component of Premarin, could produce an estrogen metabolite in the form
of a catechol which in the presence of oxidative enzymes or metal ions,
could readily form the novel and stable adducts upon a DNA helix. Such
an adduct, like any typical chemical carcinogen, can alter the replication
route of DNA, cell proliferation, and eventually will trigger the development
of cancerous gorwths in human cell.
Thus estrogen as a class can potentially
promote cancer in human reproductive organs like uterus or breast by two
different routes:
1. Combining with estrogen receptors
to stimulate abnormal cell proliferation.
2. Or reacting chemically with DNA chains,
altering the genetic codes they carry, adversely affecting their replications
and cell growths.
Estrogen induces the increase in estrogen
receptors which in turn induce the cancerous growths in reproductive organs.
The adverse effects of estrogen can be permanent and irreversible to both
mother and her offspring's, even a woman only took birth control pills
which is loaded with estrogen and progestogen for such a short time as
six months. When being exposed to a continuously high level of hormones,
the body and its reproductive system might be altered and adapt to those
extremely high levels of artificial hormones which, contrarily to the natural
hormones, tend to be long-lasting and stored in fatty tissues . That means
that the body might continue to response only to the high level of
hormones but not to the much lower level which was previously and
naturally existed. That also means that the body might continue generating
an unusually high level of estrogen or hormones for the reproductive systems
to function (abnormally) at least for a short time ( This assumption need
to be verified as it can be varied from one individual to another and with
age). These adverse effects combined with the weakened immune systems due
to aging, unbalanced diet, and abuse of modern medicine especially
antibiotics will trigger a dramatic increase in the risk of developing
cancers which occur only in reproductive organs such as breast, cervix,
prostrate, etc. Majority of women having breast cancer are 50 or
older.
The adverse effects mentioned above
are much more damaging to a developing fetus.
If you take birth control pills on a
regular basis, may God bless you and your children.
Please go to MY
HOMEPAGE ( Please bookmark or write down the address of this
page on toxicology/carcinogenecity of hormones before leaving it ).
HUMAN REPRODUCTIVE
SYSTEM:
The development of sexual characteristics and the
control of reproductive system in human body are governed by hormones which
are the chemicals secreted in very minute levels, from specialized cells,
usually in ductless gland called endocrine gland. Adult males have the
male hormone called testosterone which is responsible for the sexual characteristics
and the reproductive system in human male. Adult females have progesterone
which governs and supports a normal pregnancy plus the estrogen which regulate
the ovulation cycle. Testosterone and progesterone which are characterized
as androgens have very similar chemical structure of a steroid-cyclic ketone.
On the other hand, the estrogen which exist in female body have the chemical
structure of a steroid but a phenolic end instead of cyclic ketone. All
these hormones have a very distinct chemical structure which is common
to steroids. Since they have a distinct "shape", these hormones act as
a key which would fit perfectly into the estrogen or progesterone receptors
which act as a lock located on biological cells. When the estrogen molecules
combine with the estrogen receptors, a chain of biochemical reactions or
activities shall take place such as DNA replication or protein synthesis
( The same mechanism probably could be used to explain why the growth hormones
were used to increase meat and milk production in cattle and poultry ).
The receptor populations , which were found to concentrate around the cancerous
cells, depends directly on the levels of hormones. Thus the prostratic
androgen ( testosterone ) receptors and uterine estrogen receptors levels
relate directly to the levels of androgen and estrogen in human blood.
However, the progesterone receptors in uterus increase on the administration
of estrogen but decline rapidly following a progesterone treatment.
ABORTION AND CANCER:
( These information's were taken from NRL News
issued on August 12, 1997.)
CONTRACEPTIVE
CHEMICALS & ABORTIFACIENTS:
Birth-Control Pills:
Birth-Control (BC) pills usually contain about 0.1
mg of mestranol, a synthetic analog of the natural estrogen, and about
2.0 mgs of either norethynodrel or norethinodrone, the synthetic analogs
of progesterone. The administration of BC pills shall trick the female
body from producing the natural hormones resulting in no egg formation
or no further development of a fertilized egg ( an abortion at the earliest
stage). Thus, to all prolife
Christian men and women, chemical abortions indeed
can occur with birth control pill.
Morning - After Pill :
Morning - After Pill is the same as birth control
pill used at much higher doses. Thus the effect is much more severe toward
the mother and her offspring. Remember that the effect of this pill to
prevent conception or pregnancy is only 75% and this method is not effective
if the conception already takes place.
RU-486 ( Mifepristone ):
RU-486 or Mifepristone is an abortifacient or abortion-inducing
chemical, an anti-progesterone or anti-androgen. It is the synthetic analog
of the natural female hormone, progesterone. Mifepristone has very similar
chemical structure as the natural progesterone but functions much differently.
Progesterone is the key hormone in adult female body to establish and maintain
a normal pregnancy. RU-486 due to the similar structure will trick the
body to accept it instead of progesterone and due to its high dose ( of
anti-progesterone ), the body will stop secreting the natural hormone which
is vital in nurturing the embryo which consequently will die away in the
uterus. If Mifepristone is used in combination with a prostaglandin which
induces uterus contraction, abortion will be about 95% effective. Mifepristone
is recommended to be used for two days at 600 mgs level which equals to
10,000,000 ppt or about million time higher than the normal level in adult
female body!
Prostaglandins:
Prostaglandins are the class of powerful hormones
in which Misoprostol is one. Prostaglandin exists in human body at very
low levels similar to other hormones. Prostaglandin is used in combination
with other abortifacients such as RU-486 to induce the contraction of smooth
muscles or uterine contraction to expel aborted fetus. The toxicity or
side effect of prostaglandins is still unclear; however, just like other
hormones, introducing a large dose of artificial chemicals can result in
serious health consequences.
Methotrexate / Misoprostol:
Methotrexate and Misoprostol were recently introduced
as the new abortifacients. Being used in combination, these two drugs induce
abortion in a similar fashion as RU-486 and prostaglandin combination.
Methotrexate by itself is highly toxic, non-steroid chemical which is used
in cancer chemotherapy. It has an LD50 (rat) of 14 mgs/kg, equivalent to
sodium cyanide, a violent poison! It interferes with DNA synthesis or replication.
It greatly affects malignant cells, fetal cells, bone marrow, intestinal,
and urinary bladder. Due to its strong interference toward DNA replication,
one can reasonably anticipate that methotrexate might induce the development
of cancerous cells.
NATIONAL TOXICOLOGY
PROGRAM:
Every two years the National Toxicology Program (
NTP ) of Department of Health and Human Services ( HHS ), publishes a list
of carcinogens, dividing them into two categories:
in studies on human.
2. Substances " reasonably anticipated to be
human carcinogens " which produced
tumours in clinical
animals.
- Diethylstilbestrol (DES),
- Progesterone,
- 17-Beta Estradiol,
- Estrone,
- Mestranol,
- Ethinylestradiol
ESTROGEN-MIMICKING
ISSUE:
Endocrine disrupter: endocrine modulator, or estrogen
mimicks like DDT, PCB are chemicals that mimick, block, or disrupt the
action or production of the natural hormones. They might be named also
as anti-androgen, androgen (progesterone ) antagonist of which RU-486 (Mifepristone
) is one example.
-Causing cancers in reproductive systems,
-Producing reproductive defects in developing
offspring's or fetus,
-Birth defects, cancer in offspring's, sexual
disorientation's,
-Irreversible effects.
ESTROGEN
AND DNA:
Genetic informations or codes required
to replicate cells in a living organism are stored in DNA's or deoxyribonucleic
acids found in the chromosones of cells. DNA is a significant component
of a cell nucleus. DNA and the related RNA or ribonucleic acid control
the synthesis of proteins and many metabolic enzymes in a human body. A
DNA molecule has the conformation of a double helix consisted of two strands
of polynucleotide chains. DNA replicates or multiplies itself by separating
those two intertwining strands from which new DNA double helices are formed.
The new DNA molecules then initiate the genetic codes for the synthesis
of new cells.
FINAL
THOUGHTS ON ESTROGEN ISSUE:
It is now evident that estrogen can induce
cancerous growths in reproductive system at very minute level regardless
of the contradictory evidences or studies that the " health experts" or
pro-abortion groups want to convince women. The risk is there for women
and their offspring's. Every year there are 150,000 children born with
severe birth defects, mostly due to hormones that their mothers have taken,
not due to the environmental pollution that the press and "experts" claimed
as these birth defects are centered around the endocrine system and have
increased dramatically since birth control pills were introduced. More
cancers and rare physiological orientations now happen to children at very
early age, especially with their reproductive systems and sexual orientation.
The adverse effect might not surface until the children become adult.
ENVIRONMENTAL IMPACT:
Estrogen usage of American women can cause
a great concern on the discharge of estrogens coming from their urine into
sewage and waterways. As we already know that even the minute level of
parts per trillion can affect reproductive and endocrine systems of men
and animals. Fish and other marine life forms can be greatly vulnerable
to this modern pollution. Japan still ban the usage of birth control pills
due to potential health hazards and environmental pollution.
WORLDWIDE
CONSEQUENCE OF ABORTION:
Abortion shall bring about the Divine Chastisements
in the form of World War III ( 1999 - 2028 ) in which Russia and Iran-led
Muslims shall attack European NATO using nuclear and chemical weapons.
And China shall start her warring campaign around 2025 AD. One-thirds of
mankind shall perish.
MY HOME PAGE ON ABORTION:
Please go to abortion2.htm
A NATURAL AND EFFECTIVE METHOD OF BIRTH CONTROL and
OTHER LINKS:
